. Author manuscript; available in PMC: 2012 Oct 1.

Published in final edited form as: Pharm Res. 2011 Jun 15;28(10):2599–2609. doi: 10.1007/s11095-011-0489-3

Table I.

Evaluation of Microencapsulation of Fenretinide in Solubilizer-Free and Solubilizer-Loaded Eudragit® RS PO/RL-PO Films

Patch formulation	Fenretinide loading (wt%)		Loading efficiency (%)^a

	Theoretical^b	Actual^a
Eudragit® RS-PO	5.0	4.5 ± 0.1	90.0 ± 1.2
Solubilizer-free Eudragit® RL-PO	5.0	4.6 ± 0.1	92.1 ± 1.0
	10.0	9.2 ± 0.2	92.0 ± 2.0
Solubilizer-loaded Eudragit® RL-PO
20 wt% Tween® 20	5.6	5.4 ± 0.1	96.3 ± 1.5
20 wt% Tween® 80	5.1	4.9 ± 0.2	95.1 ± 1.6
20 wt% Brij® 98	5.2	4.8 ± 0.1	92.3 ± 1.5
20 wt% Sodium deoxycholate	5.6	5.5 ± 0.2	97.0 ± 1.0
40 wt% Sodium deoxycholate	5.0	4.6 ± 0.1	91.4 ± 1.0
20 wt% Tween® 80 + 40 wt% Sodium deoxycholate	4.9	4.5 ± 0.2	92.0 ± 2.1

Mean ± SE, n = 3

Based on polymer + excipients weight