. Author manuscript; available in PMC: 2012 Sep 1.

Published in final edited form as: Mol Genet Metab. 2011 Jul 12;104(1-2):167–173. doi: 10.1016/j.ymgme.2011.07.001

Table 1.

RYR1 Mutations and Variants Evaluated by Microarray Analysis n=34

Mutations functionally proven to be disease-causing by the European Malignant Hyperthermia Group (EMHG)

^**

Variants that have met certain EMHG criteria for pathogenicity but are still being validated

^***

Variants recently reported as associated with MHS but not yet validated as disease-causing

^****

Variants recently reported that are likely to be neutral polymorphisms