Skip to main content
. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Aug 11;21(19):5711–5714. doi: 10.1016/j.bmcl.2011.08.032

Table 1.

Alkyl pyridinium salts and N-oxides derivatives 1–9 via Scheme 1

graphic file with name nihms318081t1.jpg
Compound R Ke CB1 (µM) Yield %a
5 graphic file with name nihms318081t2.jpg 0.117 90%
6 graphic file with name nihms318081t3.jpg >10 55%
7 graphic file with name nihms318081t4.jpg 1.39 70%
8 graphic file with name nihms318081t5.jpg 0.384 91%
9 graphic file with name nihms318081t6.jpg 8.41 61%
10 graphic file with name nihms318081t7.jpg 1.20 99%
11 graphic file with name nihms318081t8.jpg 0.980 19%
12 graphic file with name nihms318081t9.jpg 8.59 16%
13 graphic file with name nihms318081t10.jpg 4.58 20%
a

Yield of the final step only.