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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Neurochem. 2011 Sep 1;119(1):240–250. doi: 10.1111/j.1471-4159.2011.07415.x

Figure 2.

Figure 2

Distribution of receptors labeled by [125I]A-85380 autoradiography in brain sections from SHR and WKY (A). Quantitative analysis of [125I]A-85380 binding in brain regions from SHR and WKY (B). Two-way ANOVA revealed a significant effect of rat strain (p < 0.0001), with approximately 30% lower [125I]A-85380 binding overall in SHR compared to WKY. Sections were incubated with 200 pM [125I]A-85380 for 45 min. Each value represents mean ± SEM of 5 to 6 rats. Cx, cerebral cortex; Cg, cingulate cortex; Cpu, caudate putamen; Acb, accumbens nucleus; Ml, molecular layer of dentate gyrus; Sl-m, stratum-lacunosum molecular; Mhb, medial habenular nucleus; Th, thalamus; Amy, amygdala; Hyp, hypothalamus; Snc, substantia nigra compact part; Cb, cerebellum. Two-way ANOVA revealed a