Table 3.

Cognitive Domains Z-Score^* (Mean ± S.E.) for SN and HIV subjects with and without APOEε4

	SN Control APOEε4− (n=54)	SN Control APOEε4+ (n=16)	HIV+ APOEε4− (n=47)	HIV+ APOEε4+ (n=22)	One-way ANOVA effect size (η2)	One-way ANOVA p-value
Fluency	0.25 ± 0.09	0.54 ± 0.15	0.26 ± 0.10	−0.17 ± 0.14	0.08	0.01c, e, f
Executive Functions	0.06 ± 0.11	0.18 ± 0.19	−0.02 ± 0.15	−0.59 ± 0.16	0.07	0.02c, e, f
Speed of Information Processing	0.02 ± 0.09	0.18 ± 0.16	−0.18 ± 0.11	−0.49 ± 0.16	0.08	0.01c, e
Attention/Working Memory	0.15 ± 0.09	−0.08 ± 0.18	−0.45 ± 0.12	−0.76 ± 0.16	0.18	<0.001b, c, e
Learning	0.21 ± 0.09	0.52 ± 0.12	−0.03 ± 0.12	−0.48 ± 0.20	0.14	<0.001c, d, e, f
Memory	0.18 ± 0.11	0.65 ± 0.13	−0.11 ± 0.12	−0.36 ± 0.17	0.13	<0.001a, c, d, e
Motor Skills	−0.01 ± 0.12	0.33 ± 0.20	−0.23 ± 0.15	−0.27 ± 0.21	0.04	0.15
Global	0.12 ± 0.06	0.33 ± 0.10	−0.11 ± 0.08	−0.45 ± 0.11	0.18	<0.001b, c, d, e, f

^*Z-scores are adjusted for age and education

^ap<0.05 for SN Control APOEε4+ > SN Control APOEε4−

^bp<0.05 for HIV+APOEε4− < SN Control APOEε4−

^cp<0.05 for HIV+APOEε4+ < SN Control APOEε4−

^dp<0.05 for HIV+APOEε4− < SN Control APOEε4+

^ep<0.05 for HIV+APOEε4+ < SN Control APOEε4+

^fp<0.05 for HIV+APOEε4+ < HIV+APOEε4−