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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Mol Cell Endocrinol. 2011 Jul 27;345(1-2):88–96. doi: 10.1016/j.mce.2011.07.024

Figure 9. Restoration of blood insulin and C-peptide levels with bone marrow stem cell and SDF-1 treatment.

Figure 9

(A) A significant increase in plasma insulin levels occurred in SDF-1+BMT treated animals compared to diabetic mice prior to BMSC transplant and/or pancreatic injections. Treatment with saline, SDF-1 or BMT alone failed to increase plasma insulin levels after induction of diabetes. Data represents mean + s.e.m. (n=6–10 mice/group; **P<0.05 compared to STZ group). (B) There was also a significant increase in C-peptide levels in plasma of SDF-1+BMT mice compared to diabetic mice. These results indicate insulin production similar to non-diabetic controls (n=6–10 mice/group; **P<0.05 compared to STZ group).