Table 2B. Total Targeted CFTR and SPINK1 Genotyping Results.

Carrier rates of each mutation in SPINK1 (N34S, P55S, any) or CFTR (F508del, R75Q, 1584GtoA, T5-TG12) are represented as a fraction of total subjects genotyped and (columns 2, 3). Carrier rates of CFTR mutations within the subset of SPINK1 mutation carriers are expressed in fraction of carriers (columns 4, 5) and fraction of total subjects (columns 6,7)

Mutation	Patients (%)	Controls (%)	Patients w/SPINK1 mut(%)	Controls w/SPINK1 mut(%)	Co-inheritance Patients (%)	Co-inheritance Controls (%)
N34S	27/80 (33.8)	20/653 (3.1)
P55S	5/80 (6.2)	1/653 (0.2)
any SPINK1	29/80 (36.2)	21/653 (3.2)	7/29 (24.1)	0/21
F508del	7/80 (8.8)	22/653 (3.4)	4/29 (13.8)	0/21	4/80 (5.0)	0/653 (0)
R75Q	13/80 (16.2)	35/653 (5.7)	6/29 (20.7)	1/21 (4.7)	7/80 (8.8)	1/653 (0.2)
1584GtoA	7/80 (8.8)	28/653 (4.3)	5/29 (17.2)	3/5 (60.0)	4/80 (5.0)	3/150 (2.0)
IVS8 T5-TG12	4/80 (5.0)	4/150 (2.7)	1/29 (3.4)	0/5	1/80 (1.2)	0/150 (0)