Table 4.

Genotype and allele frequencies of RPSA polymorphisms in controls and sporadic CJD patients

	5'-UTR -8T>C		134-32C>T		519G>A		793+58C>T
	Controls (n = 189)	Sporadic CJDs (n = 180)	Controls (n = 50)	Sporadic CJDs (n = 50)	Controls (n = 50)	Sporadic CJDs (n = 50)	Controls (n = 50)	Sporadic CJDs (n = 50)
Genotype
1/1	91 (48.2%)	87 (48.3%)	33 (66.0%)	33 (66.0%)	34 (68.0%)	33 (66.0%)	28 (56.0%)	24 (48.0%)
1/2	77 (40.7%)	78 (43.3%)	15 (30.0%)	15 (30.0%)	14 (28.0%)	15 (30.0%)	12 (24.0%)	22 (44.0%)
2/2	21 (11.1%)	15 (8.4%)	2 (4.0%)	2 (4.0%)	2 (4.0%)	2 (4.0%)	10 (20.0%)	4 (8.0%)
P-value	0.646		1.000		1.000		0.058
Allele
1	279 (0.70)	252 (0.70)	81 (0.81)	81 (0.81)	82 (0.82)	81 (0.81)	68 (0.68)	70 (0.70)
2	119 (0.30)	108 (0.30)	19 (0.19)	19 (0.19)	18 (0.18)	19 (0.19)	32 (0.32)	30 (0.30)
P-value	0.976		1.000		0.856		0.760

For columns '1' refers to the more common genotype or allele and '2' to the less common genotype or allele of each polymorphism.