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. Author manuscript; available in PMC: 2012 Aug 8.
Published in final edited form as: Biomacromolecules. 2011 Jul 18;12(8):2933–2945. doi: 10.1021/bm2005214

Table 3.

Summary of the Mineralization Results. L- length, W- width, T- thickness; * Size varies in a concentration-dependent manner; ** dimension as % of control

Mineralization Experiment Mineral Phase Mineral Shape and Size Mineral Organization
No proteins (control) Apatitic Plates
L=143 nm
W= 80 nm
T= 3 nm
Random
DMP1 alone Apatitic Plates*
L= 66-116 nm (46-81 %)**
W= 34-67 nm (42-96%)
T= 3 nm (100%)
Random
DPP alone ACP at high concentrations Spheres ∼ 60-70 nm Large spherical aggregates
Apatitic at lower concentrations Plates*
L= 59-114 nm (41-79%)
W= 36-61 nm (45-76 %)
T= 3 nm (100%)
Random
p-DMP1 alone Apatitic Plates*
L= 74-39 nm (51-27%)
W= 39-22 nm (48-27%)
T= 3 nm
At higher concentrations, crystallites form parallel arrays with their c-axes coaligned
p-DPP alone Inhibits mineral formation at higher concentrations Nanodots ∼4 nm Random
Apatitic at lower concentrations Plates
L= 60-70 nm (41-48%)
W= 40-51 nm (50-63 %)
T= 3 nm
Random
DMP1 with collagen fibrils Apatitic Plates
L= 66 nm (46%)
W= 34 nm (42%)
T= 3 nm (100%)
Random
DPP with collagen fibrils ACP Spheres ∼60-70 nm Large spherical aggregates
p-DMP1 with collagen fibrils Apatitic Plates Mineralized collagen fibrils with parallel crystalline arrays coaligned with the fibril axis, the mineral is located both intra- and extrafibrillarly
p-DPP with collagen fibrils Apatitic Plates Mineralized collagen fibrils with parallel crystalline arrays co-aligned with the fibril axis, the mineral is located intrafibrillarly