Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2011 Sep 13.

Published in final edited form as: Lancet Oncol. 2010 May 5;11(6):543–552. doi: 10.1016/S1470-2045(10)70090-5

Table 4.

Multivariable analysis of prognostic factors

Factors	EFS			OS

	HR	95% CI	P-value	HR	95% CI	P-value
Treatment Arm	0.83	(0.50, 1.39)	0.483	0.83	(0.46, 1.53)	0.554
Induction I MRD ≥ 1%	2.41	(1.36, 4.26)	0.003	2.11	(1.09, 4.11)	0.028
CBF	0.32	(0.13, 0.79)	0.013	0.37	(0.12, 1.12)	0.079
Age at diagnosis^a	1.65	(0.92, 2.95)	0.095	2.55	(1.23, 5.27)	0.012
Other 11q23	2.05	(0.96, 4.34)	0.062	3.29	(1.34, 8.04)	0.009
M7 without t(1;22)	2.17	(0.86, 5.45)	0.099	5.64	(1.99, 16.0)	0.001
FLT3-YTD	1.64	(0.82, 3.27)	0.163	1.93	(0.84, 4.44)	0.123

Abbreviations: EFS, event-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; ITD, internal tandem duplication;

^a

Age at diagnosis is dichotomized as less than or great than 10 years.