Figure 6.

Effect of ectopic Xvax1 overexpression on the transcription of Xrx. Normal expression pattern of Xrx at stages 17 (a) and stage 34 (g). A horizontal vibratome section of a stage 17 embryo is shown in d (anterior is up). Embryos were injected with 250 pg (b,e,h) or 500 pg [c,d(is),f,i] of Xvax1 encoding mRNA into both blastomeres at the two-cell stage. The resulting effects were dose dependent. At stage 17, repression of Xrx is either moderate (b,e) or strong [c,d(is),f], resulting in a mild (h) or strong phenotype (i) at stage 34. (nis) Noninjected side; (is) injected side.