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Population variability of hepatic CYP1A2 expression phenotypes (n = 150).
| RNA CYP1A2/ RPLP0 relative units | Protein content pmol/mg | Phenacetin-O-deethylation pmol/min/mg | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Minimum | 0.03 | 3.62 | 130.1 | ||||||
| Median | 1.00 | 64.7 | 1442 | ||||||
| Maximum | 5.88 | 278.7 | 4536 | ||||||
| Ratio maximum/ minimum | 196 | 77.4 | 34.9 | ||||||
| Normal distribution | No | No | No | ||||||
| Coefficient of variation (cv, %) | 77.2 | 69.3 | 56.2 |
