Table 6.
Conditional logistic regression models for tuberculosis recurrence
| Characteristic | Cases (n = 20) n (%) |
Controls (n = 78) n (%) |
Unadjusted | Adjusted* | ||
|---|---|---|---|---|---|---|
| Odds ratio (95%CI) | P value | Odds ratio (95%CI) | P value | |||
| HIV infection | 6 (30) | 12 (15) | 2.67 (0.77–9.18) | 0.12 | 5.01 (1.07–23.39) | 0.04 |
| Chronic lung disease | 8 (40) | 13 (17) | 4.01 (1.15–13.94) | 0.03 | 5.28 (1.16–24.04) | 0.03 |
| White race | 12 (60) | 28 (40) | 4.01 (1.15–14.00) | 0.03 | 4.62 (1.28–16.68) | 0.02 |
| Male sex | 18 (90) | 47 (60) | 6.47 (1.39–30.26) | 0.02 | ||
| Body mass index, kg/m2, median [IQR] | 20.0 [18.7–22.1] | 21.3 [18.8–24.4] | 0.94 [0.83–1.07] | 0.38 | ||
| Tobacco use | 17 (85) | 39 (50) | 16.85 (2.06–137.76) | 0.008 | ||
| Cavitary or bilateral disease and culture positive at 2 months | 13 (65) | 46 (59) | 1.33 (0.47–3.71) | 0.59 | ||
| Time to completion of therapy, weeks, median [IQR] | 39 [27–46] | 35 [27–41] | 1.00 [0.96–1.03] | 0.78 | ||
*
All covariates in the table were included in the disease risk score except for the exposure of interest and tobacco use, due to collinearity with chronic lung disease.
CI = confidence interval; HIV = human immunodeficiency virus.