Table 2.
CBF ROI | ||
---|---|---|
CBF (ml/100 ml/min) | R2* (s−1) | |
Pre-caffeine (baseline) | 82.6 (4.4) | 24.4 (1.1) |
Pre-caffeine (stimulus) | 124.6 (5.2)* | 23.9 (1.1)* |
Post-caffeine (baseline) | 59.9 (3.5)* | 27.1 (1.2)* |
Post-caffeine (stimulus) | 93.6 (4.8)* | 26.6 (1.2)* |
Mean (one s.e.m., *p<0.001), absolute values of CBF and measured in the pre- and post-caffeine experiments (10 subjects). ‘Baseline' isa veraged over the 10 s prior to the start of the stimulus during which a gray background with a white square in the middle was presented. The stimulus response was averaged over the last 10 s of the stimulus and denotes the steady state response to the flashing checkerboard visual stimulus. Significance for the pre-caffeine stimulus response and the post-caffeine baseline shift were tested against the pre-caffeine baseline. Significance for the post-caffeine stimulus response was testing against the post-caffeine baseline.