Table 1.
Anatomical characteristics of A-ZIP/F-1 mice
|
|
Body weight (grams)
|
Length (cm)
|
BMI (grams/cm2)
|
Epi WAT (%)
|
BAT (%)
|
Liver (%)
|
Kidney (%)
|
Spleen (%)
|
Heart (%)
|
|---|---|---|---|---|---|---|---|---|---|
| A-ZIP/F-1 | 37.6 ± 0.9 | 9.68 ± 0.07 | 0.401 ± 0.006 | <0.025 | 0.07 ± 0.01 | 9.51 ± 0.70 | 2.15 ± 0.06 | 0.58 ± 0.07 | 0.50 ± 0.01 |
| Wildtype | 39.5 ± 1.1 | 9.90 ± 0.06 | 0.402 ± 0.007 | 2.83 ± 0.18 | 0.67 ± 0.05 | 4.49 ± 0.09 | 1.37 ± 0.03 | 0.32 ± 0.01 | 0.42 ± 0.02 |
| Ratio | 0.95 | 0.98 | 1.00 | <0.01 | 0.11 | 2.12 | 1.57 | 1.81 | 1.18 |
| P | 0.23 | 0.08 | 0.93 | 0.0002 | 0.002 | 0.0002 | 0.02 | 0.01 |
Data are mean ± s.e.m. with five mice in each group. Animals were 20-week-old males from two litters. The body mass index (BMI) is the weight/(length squared). The organ weights were measured as a percentage of the animal’s body weight. For epididymal (Epi) WAT, we estimate that 10 mg of tissue is the limit of detection. Ratio is the A-ZIP/F-1 value expressed as a fraction of the wild-type value. Probabilities (P) are from two-tailed t-test.