. Author manuscript; available in PMC: 2011 Sep 13.

Published in final edited form as: Am J Med Genet A. 2010 Aug;152A(8):1994–2001. doi: 10.1002/ajmg.a.33509

TABLE I.

Biochemical Parameters at Baseline and After 12 months of Supplements (n = 48 at 12 Months)

		Betaine (μmol/L)	DMG (μmol/L)	RBC folate (ng/ml)	Creatine (μmol/L)	Meth (μmol/L)	Hcy (μmol/L)	GAA (μmol/L)
Placebo group	Baseline (n = 29)	51.45	9.26	614.45	58.43	50.83	5.37	1.202
	12 months (n = 28)	79.52	12.96	746.17	49.49	20.13	3.74	1.045
Treatment group	Baseline (n = 24)	58.41	10.74	638.54	71.36	58.41	6.40	1.148
	12 months (n = 20)	599.69^a	64.72^a	894.95^a	47.73	29.02	3.45	1.296

Statistically significant difference from placebo at p <0.05.