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EPAS1 expression in adult carotid body. (A) Whole-mount staining of adult (age, 2.5 months) heterozygote showing intense β-gal expression in the carotid body (CB), which is located at the bifurcation of the common carotid artery (CC) into the internal carotid (IC) and external carotid (EC) arteries. (B,C) Adjacent histological sections revealing expression in the endothelial and type I cells of the carotid body. Bar, 100 μm (B); 50 μm (C).
