Table 1.
Age (dpc)
|
+/+
|
+/−
|
−/−
|
Status of mutant embryosa
|
---|---|---|---|---|
9.5 | 15 (30%) | 27 (54%) | 8 (16%) | 8 alive |
10.5 | 36 (26%) | 80 (57%) | 24 (17%) | 20 alive, 2 dead, 2 uk |
11.5 | 29 (25%) | 62 (53%) | 26 (22%) | 24 alive, 1 dead, 1 uk |
12.5 | 25 (21%) | 69 (58%) | 25 (21%) | 17 alive, 7 dead, 1 uk |
13.5 | 38 (22%) | 102 (58%) | 35 (20%) | 15 alive, 19 dead, 1 uk |
⩾14.5 | 8 (24%) | 18 (55%) | 7 (21%) | 7 dead |
Newborn | 104 (32%) | 225 (68%) | 0 |
Status of mutant embryos: alive, presence of heartbeat; dead, no heartbeat, and in more advanced cases, blood coagulation and tissue necrosis was observed. Cases where the embryo appeared viable, but heartbeat was absent are defined as unknown (uk).