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. 2011 Sep 13;6(9):e24844. doi: 10.1371/journal.pone.0024844

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Chung et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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PrP^Sc level in the spleen at 60 dpi. At this time, there is peripheral replication of PrP^Sc but CNS invasion has not yet occurred. Spleen homogenates for each group (n = 10) were tested for levels of PrP^Sc and plotted with the vehicle level represented as 100% infectivity. Differences between each treated group versus the control group were not significant.