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. Author manuscript; available in PMC: 2012 Sep 20.
Published in final edited form as: Biochemistry. 2011 Aug 24;50(37):8078–8089. doi: 10.1021/bi2006652

Figure 2. Npm2- and Np-core pentamers.

Figure 2

(A) The Npm2-core pentamer is shown as a ribbon representation viewed from the top. Approximate positions of β-hairpin tips are indicated with dotted loops, since they are not well ordered. (B) Two independent Npm2-core pentamers in the asymmetric unit are over-layed. (C) A perfect Np-core pentamer with 5 β-hairpins (in red) 9 is shown over-layed with the human Npm2-core pentamer from panel A (in blue). (D) An electrostatic surface is shown of three adjacent subunits within the Npm2-core pentamer. The exposed subunit-subunit interface is non polar (see dashed outlines).