Table 2.
p Values for Genes Expression in Hearts of Normal (N) and Growth Hormone Receptor/–Binding Protein Knockout (GHRKO; KO) Mice Fed AL or Subjected to 40% CR
Gene |
p Value |
|||||
A vs B | C vs D | A vs C | B vs D | AB vs CD (N vs KO) | AC vs BD (AL vs CR) | |
PGC-1α | NS | NS | NS | NS | NS | NS |
AMPK | NS | NS | NS | <.001 | .001 | NS |
SIRT-1 | NS | NS | NS | NS | .037 | NS |
SIRT-3 | NS | NS | NS | .002 | .011 | NS |
eNOS | NS | NS | NS | NS | .024 | NS |
NRF-1 | NS | NS | NS | NS | NS | NS |
TFAM | NS | NS | NS | NS | NS | NS |
MFN-2 | NS | .029 | NS | .003 | .028 | NS |
COXIV | NS | NS | .003 | NS | <.001 | NS |
Note: A represents N-AL mice, B represents N-CR mice, C represents KO-AL mice, and D represents KO-CR mice. AL = ad libitum; CR = calorie restriction; NS = not significant.