Table 4.

Performance on Key Cognitive Indices (mean ± SD), for Responders (Resp) and Non-responders (Non-resp), for each Treatment Arm

	Lamotrigine treatment				Placebo treatment
	Resp (n=7)	Non-resp (n=9)	Sig.	E	Resp (n=5)	Non-resp (n=11)	Sig.	E
IED Total errors	22.86 ± 12.46	11.22 ± 7.28	*	1.18	14.6 ± 9.4	15.44 ± 10.51		−0.08
IED Total errors (adjusted)	33.57 ± 24.58	14 ± 15.48	*	0.98	14.6 ± 9.4	15.44 ± 10.51		−0.08
IED Total errors, ID shift	0.43 ± 0.79	0.22 ± 0.44		0.34	3.2 ± 7.16	0.33 ±0.71		0.69
IED Total errors, ED shift	15.14 ± 11.33	4.89 ± 7.3	*	1.11	4.8 ± 5.81	6.11 ± 6.77		−0.20
SST Median correct RT on GO trials	551 ± 196.74	438.78 ± 128.1		0.70	508.4 ± 218.93	486.72 ± 125.61		0.13
SST SSRT	211.55 ± 44.83	164.38 ± 23.83	**	1.37	294.43 ± 158.18	167.7 ± 51.23	*	1.26
SST Proportion of successful stops	0.54 ± 0.1	0.51 ± 0.04		0.42	0.51 ± 0.21	0.52 ± 0.09		−0.07
SST Direction errors on stop and go trials	3.57 ± 3.69	4 ± 4.9		−0.10	6.6 ± 11.13	3 ± 5.94		0.45

Sig.: Significant difference between responders and non-responders within group,

^*p<0.05,

^**p<0.01 E: Effect size, Cohen’s D, using pooled standard deviation