Type: Early Transient
Wheezing
Presentation:
Lung function diminished at birth
and remains reduced at age 6 and
11 |
Risk Factors:
Maternal smoking during pregnancy Post-natal exposure to tobacco smoke Prematurity No family history of asthma or atopy No peak flow variability or methacholine responsiveness No elevated serum IgE or skin test reactivit
|
Type: Atopic Persistent
Wheezing
Presentation:
Normal lung function at birth with
diminished (lowest) lung function
at age 6 and 11 |
Risk Factors:
Maternal asthma, maternal smoking Genetic pre-disposition for sensitization to aero-allergens Allergic sensitization and chronic airway inflammation<1 year Atopy, elevated serum IgE at 9 months of age and at age 6, but not in cord blood Eczema, rhinitis apart from cold Early onset wheezing and severe disease Peak flow variability and methacholine responsiveness
|
Type: Non-atopic Persistent
Wheezing
Presentation:
Normal lung function at birth with
diminished lung function at age 6 |
Risk Factors:
Maternal smoking Lower respiratory illnesses in the first 3 years RSV before 3 years of age associated with wheeze at age 10 Peak flow variability but no methacholine responsiveness
|
Type: Late Onset Wheezing
Presentation:
Normal lung function at birth and
at age 6 |
Risk Factor:
|
