TABLE 3.
82Rb Organ-Absorbed Dose per Unit Administered Activity
| Target organ | Absorbed dose (mGy/MBq) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RB001 | RB002 | RB003 | RB004 | RB005 | RB006 | RB007 | RB008 | RB009 | RB010 | Mean | SD | Coefficient of variation (%) | |
| Adrenals | 1.83E−03 | 2.07E−03 | 2.15E−03 | 2.22E−03 | 2.36E−03 | 8.35E−04 | 2.69E−03 | 2.24E−03 | 1.75E−03 | 2.79E−03 | 2.09E−03 | 5.50E−04 | 26 |
| Brain | 8.17E−05 | 3.00E−04 | 2.02E−04 | 1.89E−04 | 2.21E−04 | 1.05E−04 | 1.09E−04 | 2.08E−04 | 1.43E−04 | 1.59E−04 | 1.72E−04 | 6.57E−05 | 38 |
| Breasts | 3.53E−04 | NA | NA | NA | 1.83E−04 | NA | NA | 1.87E−04 | 2.52E−04 | 1.90E−04 | 2.33E−04 | 7.28E−05 | 31 |
| Gallbladder wall | 1.10E−03 | 4.99E−04 | 6.38E−04 | 7.51E−04 | 8.55E−04 | 5.40E−04 | 5.89E−04 | 1.06E−03 | 9.88E−04 | 1.30E−03 | 8.32E−04 | 2.72E−04 | 33 |
| LLI wall | 1.01E−03 | 4.60E−04 | 4.87E−04 | 6.59E−04 | 8.40E−04 | 9.95E−04 | 4.37E−04 | 6.54E−04 | 6.58E−04 | 7.33E−04 | 6.93E−04 | 2.06E−04 | 30 |
| SI | 2.13E−03 | 7.92E−04 | 8.32E−04 | 1.93E−03 | 1.23E−03 | 1.08E−03 | 8.89E−04 | 1.71E−03 | 9.88E−04 | 1.35E−03 | 1.29E−03 | 4.78E−04 | 37 |
| Stomach wall | 2.38E−03 | 2.52E−03 | 3.72E−03 | 1.20E−03 | 1.65E−03 | 1.01E−03 | 2.32E−03 | 2.14E−03 | 2.30E−03 | 2.75E−03 | 2.20E−03 | 7.81E−04 | 36 |
| ULI wall | 2.14E−03 | 7.74E−04 | 9.84E−04 | 1.62E−03 | 2.07E−03 | 1.04E−03 | 1.07E−03 | 1.34E−03 | 1.36E−03 | 1.51E−03 | 1.39E−03 | 4.56E−04 | 33 |
| Heart wall | 4.54E−03 | 3.05E−03 | 4.08E−03 | 4.17E−03 | 4.15E−03 | 3.32E−03 | 3.17E−03 | 4.13E−03 | 3.34E−03 | 4.62E−03 | 3.86E−03 | 5.81E−04 | 15 |
| Kidneys | 7.85E−03 | 3.76E−03 | 7.01E−03 | 6.05E−03 | 7.44E−03 | 2.66E−03 | 5.66E−03 | 5.46E−03 | 5.23E−03 | 6.93E−03 | 5.81E−03 | 1.64E−03 | 28 |
| Liver | 1.63E−03 | 7.79E−04 | 1.17E−03 | 1.21E−03 | 1.34E−03 | 5.47E−04 | 7.24E−04 | 1.16E−03 | 1.02E−03 | 1.33E−03 | 1.09E−03 | 3.28E−04 | 30 |
| Lungs | 3.45E−03 | 2.67E−03 | 2.46E−03 | 2.43E−03 | 3.36E−03 | 2.02E−03 | 2.50E−03 | 4.15E−03 | 3.08E−03 | 3.48E−03 | 2.96E−03 | 6.51E−04 | 22 |
| Muscle | 3.56E−04 | 3.29E−04 | 2.94E−04 | 2.85E−04 | 3.73E−04 | 3.48E−04 | 3.20E−04 | 3.79E−04 | 4.14E−04 | 3.75E−04 | 3.47E−04 | 4.05E−05 | 12 |
| Ovaries | 4.12E−04 | NA | NA | NA | 2.79E−04 | NA | NA | 4.71E−04 | 3.13E−04 | 3.54E−04 | 3.66E−04 | 7.69E−05 | 21 |
| Pancreas | 4.77E−04 | 1.57E−03 | 1.71E−03 | 2.97E−03 | 3.68E−03 | 1.39E−03 | 2.64E−03 | 3.26E−03 | 2.38E−03 | 3.50E−03 | 2.36E−03 | 1.05E−03 | 44 |
| Red marrow | 3.83E−04 | 2.89E−04 | 2.83E−04 | 2.92E−04 | 3.11E−04 | 2.91E−04 | 2.86E−04 | 3.30E−04 | 3.53E−04 | 3.08E−04 | 3.13E−04 | 3.32E−05 | 11 |
| Osteogenic cells | 5.81E−04 | 4.41E−04 | 4.00E−04 | 3.94E−04 | 5.32E−04 | 4.61E−04 | 4.28E−04 | 5.57E−04 | 6.15E−04 | 5.33E−04 | 4.94E−04 | 7.90E−05 | 16 |
| Skin | 3.10E−04 | 2.95E−04 | 2.59E−04 | 2.49E−04 | 3.28E−04 | 3.14E−04 | 2.86E−04 | 3.33E−04 | 3.70E−04 | 3.30E−04 | 3.07E−04 | 3.64E−05 | 12 |
| Spleen | 1.91E−03 | 1.48E−03 | 1.81E−03 | 2.96E−03 | 2.48E−03 | 8.15E−04 | 1.74E−03 | 2.10E−03 | 1.60E−03 | 2.24E−03 | 1.91E−03 | 5.86E−04 | 31 |
| Testes | NA | 2.29E−04 | 1.94E−04 | 1.81E−04 | NA | 1.29E−04 | 1.81E−04 | NA | NA | NA | 1.83E−04 | 3.59E−05 | 20 |
| Thymus | 4.11E−04 | 3.75E−04 | 3.46E−04 | 3.34E−04 | 4.26E−04 | 3.91E−04 | 3.63E−04 | 4.35E−04 | 4.60E−04 | 4.34E−04 | 3.98E−04 | 4.22E−05 | 11 |
| Thyroid | 1.67E−03 | 9.65E−04 | 1.66E−03 | 2.69E−03 | 2.12E−03 | 1.36E−03 | 1.66E−03 | 2.90E−03 | 1.37E−03 | 1.52E−03 | 1.79E−03 | 6.07E−04 | 34 |
| Urinary bladder wall | 5.92E−04 | 3.84E−04 | 3.40E−04 | 3.80E−04 | 3.81E−04 | 4.09E−04 | 3.66E−04 | 5.04E−04 | 5.15E−04 | 4.06E−04 | 4.28E−04 | 8.11E−05 | 19 |
| Uterus | 1.94E−03 | NA | NA | NA | 5.18E−04 | NA | NA | 9.36E−04 | 6.72E−04 | 9.00E−04 | 9.93E−04 | 5.56E−04 | 56 |
| Total body | 5.31E−04 | 4.21E−04 | 4.18E−04 | 4.19E−04 | 5.33E−04 | 4.22E−04 | 4.21E−04 | 5.36E−04 | 5.38E−04 | 5.33E−04 | 4.77E−04 | 6.01E−05 | 13 |
| Effective dose* (mSv/MBq) | 1.50E−03 | 1.11E−03 | 1.34E−03 | 1.13E−03 | 1.34E−03 | 8.52E−04 | 1.14E−03 | 1.48E−03 | 1.25E−03 | 1.45E−03 | 1.26E−03 | 2.04E−04 | 16 |
*
Effective dose was calculated using ICRP 103 tissue-weighting factors.
NA = not applicable.