Figure 3.

mec-10 and mec-4 mutants have MRCs with decreased amplitude. A, Examples of in vivo recordings of MRCs from PLM touch receptor neurons in wild-type, mec-10, and mec-4 animals (at −74 mV) in response to a saturating mechanical stimulus (top). Each trace is an average of 20 sweeps. Stimulus pressure is indicated above each trace. B, Maximum peak amplitude of MRC recorded from PLM touch receptor neurons (at −74 mV), at the onset (black bars) and offset (white bars) of a response to a saturating mechanical stimulus (mean ± SEM, numbers in parentheses indicate number of cells tested).