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. Author manuscript; available in PMC: 2012 Aug 4.
Published in final edited form as: J Phys Chem B. 2011 Jul 7;115(30):9431–9438. doi: 10.1021/jp204407d

FIG. 4.

FIG. 4

The heavy atom RMSD from the native structure of the β-hairpin as a function of simulation time with the effective temperature of the protein at 600K using the scaled Hamiltonian of REST2 without attempted replica exchanges. Both RMSD > 4Å and < 4Å are sampled, by comparison in REST1 only RMSD > 4Å are sampled at high temperatures.(Fig. 4 of reference 7).