Table 1. Associations between various immune cell densities of the SLN and clinicopathologic parameters of the primary tumour.
CD8 (median (IQR)) | FOXP3 (median (IQR)) | CD57 (median (IQR)) | DC-LAMP (median (IQR)) | ||
---|---|---|---|---|---|
Sex (no.) | Male (35) | 2756 (2242–3343) | 843 (496–1313) | 596 (257–944) | 403 (220–652) |
Female (29) | 2339 (2058–3480) | 974 (478–1167) | 592 (512–700) | 365 (220–561) | |
Age (no.) | ⩽65 years (49) | 2665 (2131–3323) | 843 (477–1203) | 603 (350–900) | 381 (218–632) |
>65 years (15) | 2711 (2128–3661) | 1042 (763–1313) | 590 (352–676) | 372 (266–659) | |
Lauren (no.) | Intestinal (31) | 2643 (2093–3268) | 843 (483–1237) | 562 (302–670)* | 377 (211–643) |
Diffuse (33) | 2871 (2220–3480) | 1001 (518–1296) | 676 (502–1038)* | 388 (266–644) | |
Tumour size (no.) | <3 cm | 2871 (2373–3456) | 961 (507–1186) | 588 (333–901) | 328 (207–583) |
⩾3 cm | 2298 (1984–3310) | 878 (438–1389) | 644 (368–791) | 450 (269–653) | |
pT stage (no.) | T1 (35) | 2825 (2279–3418) | 778 (418–1229) | 584 (278–689) | 372 (212–647) |
T2–4 (29) | 2515 (2030–3310) | 1001 (614–1308) | 678 (363–935) | 381 (233–636) | |
LN metastasis (no.) | No (47) | 2579 (2088–3418) | 778 (418–1074)** | 592 (369–803) | 394 (218–650) |
Yes (17) | 2892 (2221–3360) | 1127 (876–1576)** | 608 (343–976) | 297 (243–512) | |
LI (no.) | No (57) | 2659 (2128–3405) | 949 (477–1218) | 591 (370–792) | 381 (227–642) |
Yes (7) | 2772 (2172–3578) | 908 (843–1933) | 727 (291–1150) | 267 (209–660) |
Abbreviations: IQR=interquartile range (25–75%); LI=lymphatic invasion; LN=lymph node; pT=invasion depth of the primary tumour; SLN=sentinel lymph node.
Mann–Whitney U-test was used in each analysis; *P<0.05; **P<0.01.