Table 4. Frequency of prognostic clinicopathological characteristics of the 58 patients treated with trastuzumab–taxane CT, according to the presence or the absence of T-bet+ cells after CT.
Presence of T-bet+ cells
|
Absence of T-bet+ cells
|
||||
---|---|---|---|---|---|
N | % | N | % | P | |
Age (years) | |||||
<50 | 14 | 49 | 18 | 62 | |
⩾50 | 15 | 51 | 11 | 38 | 0.43 |
Tumour initial stage | |||||
T2 | 21 | 72 | 15 | 51 | |
T3–T4 | 8 | 28 | 14 | 49 | 0.17 |
Axillary nodal status | |||||
Positive | 18 | 62 | 17 | 58 | |
Negative | 11 | 38 | 12 | 42 | 0.99 |
Tumour grade | |||||
I+II | 19 | 65 | 18 | 62 | |
III | 10 | 35 | 11 | 38 | 0.99 |
Oestrogen receptor | |||||
Positive | 18 | 62 | 15 | 51 | |
Negative | 11 | 38 | 14 | 49 | 0.59 |
Pathological complete response | |||||
Yes | 15 | 51 | 9 | 31 | |
No | 14 | 49 | 20 | 69 | 0.18 |
Abbreviation: CT=chemotherapy.