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Simplified pedigrees are drawn for families 1–3. All pedigrees are compatible with autosomal dominant inheritance of the disease trait. Cobb's angles are indicated. Question marks indicate uncertain status. Several unaffected individuals who have been genotyped are not included, as they were not useful in linkage analysis. In family 2, four unaffected individuals are included, as they contributed to the mod score analysis. ND, status not determined.
