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. 2011 Mar 16;19(8):865–869. doi: 10.1038/ejhg.2011.31

Table 2. Informativity studies performed in each family.

Family No. of meioses between a common ancestor and all affected individuals Number of common ancestors Number of disease allele transmissions to affected individuals Expected maximum lod score Probabilities to reach Zimax under H0, 0, 1 or more than once in whole-genome analysis
(Fi) (Mi) (ni) (Ti=Mi-ni) (Zimax=−Ti log10(0.5)) 0 1 >1
F1 9 4 5 1.51 0.253 0.346 0.401
F2 12 2 10 3.01 0.958 0.041 0.001
F3 10 1 9 2.71 0.918 0.079 0.003

Only affected individuals have been taken into account.