Table 4. Association of PTGES genotypes with disease onset and activity in female patients with RA.
| Disease parameters | SNP | Genotype | Median (range) | Counts | P-value |
|---|---|---|---|---|---|
| Disease onset, years | rs10739757 | C | 51 (19–74) | 246 | 0.0065 |
| TT | 54 (16–82) | 1136 | |||
| DAS28, score | rs4837404 | AA | 5.57 (1.74–8.89) | 266 | 0.0080 |
| G | 5.28 (1.57–8.29) | 321 | |||
| DAS28, score | rs2302821 | C | 5.57 (2.39–8.89) | 114 | 0.0321 |
| AA | 5.31 (1.57–8.37) | 491 | |||
| DAS28, score | rs11792431 | A | 5.63 (3.82–8.89) | 63 | 0.0369 |
| GG | 5.32 (1.57–8.66) | 536 |
Abbreviation: DAS28, disease activity score.