Figure 3.

Mice (either C57BL/6 mice or DBA/2 mice) were randomly divided into 2 groups as follows: control group (control mice) and tumor group (tumor mice) (15 animals per group). PBS was injected into control mice, while mice in the tumor group were injected with tumor cells. Tumor establishment took ~ 3 weeks. Saliva, salivary gland, serum, and tumor tissues were collected from each mouse. Five mice each were pooled into one group and processed to profile their transcriptome by the expression microarrays (Gao et al., 2009).