Table 1.

Investigator assessment of severity of disease

	Placebo (n = 18)				CHD-FA (n = 18)
	Base	±SD	Final	±SD	Base	±SD	Final	±SD
Severity	2.278	0.826	1.222*	0.732	1.833	0.514	0.8331	0.707
Erythema	2.056	0.998	1.056**	0.873	1.176	0.728	0.2352	0.437
Vesiculation	0.333	0.686	0.056	0.236	0.353	0.493	0.000	0.000
Fissuring	0.056	0.236	0.056	0.236	0.000	0.000	0.000	0.000
Scaling	0.500	0.707	0.056***	0.236	0.176	0.529	0.059	0.243

^*Notes: P = 0.0009;

^**P = 0.0059;

^***P = 0.0313;

¹P < 0.0001;

²P = 0.0002 (all by Wilcoxon Signed Rank test). (0 = absent, 1 = mild, 2 = moderate, 3 = moderately severe, 4 = severe.)

Abbreviations: CHD-FA, carbohydrate-derived fulvic acid; SD, standard deviation.