Table 2.

Investigator assessment of global response to treatment

	Scale response (0–6)
	Average	±SD
Placebo (n = 18)	2.94	1.11
CHD-FA (n = 18)	1.77*	1.00

^*Notes: P < 0.05 (by Mann-Whitney U test). 0 = completely clear except for possible residual hyperpigmentation, 1 = almost clear, very significant clearance (about 90%), 2 = marked improvement/significant improvement (about 75%), 3 = moderate improvement (about 50%), 4 = slight improvement (about 25%), but significant disease remaining, 5 = no change (moderate to severe disease), 6 = worse.

Abbreviations: CHD-FA, carbohydrate-derived fulvic acid; SD, standard deviation.