Figure 6.

Histostaining of liver of mice: Effect of CXCR4 siRNAs on inhibition of colorectal cancer metastasis to liver in vivo. A) H and E staining of tumor show growth and angiogenesis in Group A. B) H and E staining of liver (original magnification 10×) in Group F without injection of tumor cells; in this group there were no infiltrative lymphocytes. C) H and E staining (original magnification 40×) of liver in Group F. D) H and E staining of liver (original magnification 40×) in Group A along with subcutaneous injection of tumor cells through tail vein, showing a lot infiltrative lymphocytes between the hepatic parenchyma and portal vein following metastasis of tumor cells to the liver. E) H and E staining (original magnification 40×) of liver in Group B. F) H and E staining (original magnification 40×) of liver in Group C. G) H and E staining (original magnification 40×) of liver in Group D. H) Hematoxylin and eosin staining (original magnification 40×) of liver in Group C. Metastases in Groups A, B, C, D, and E were compared with Group E.

Abbreviation: H and E, hematoxylin and eosin.