Table 3.

Maximum Voluntary Muscle Strength^*

	No Exercise		Exercise
	Placebo	Testosterone	Placebo	Testosterone
Leg press†
Baseline	259 (20)	252 (31)	260 (19)	255 (23)
Week 16	264 (33)	292 (30)	332 (21)	310 (28)
Change from baseline	5 (16)	40 (15)	72 (14)‡	55 (10)‡
P value	.766	.021	<.001	<.001
Bench press§
Baseline	46 (3)	48 (6)	43 (4)	45 (6)
Week 16	44 (5)	54 (5)	56 (4)	57 (6)
Change from baseline	−2 (4)	6 (2)	13 (3)‡	12 (2)‡
P value	.682	.001	<.001	<.001

^*Strength was measured, in kilograms, by the 1-repetition maximum method. The data on each day represent the mean (SEM) of all available values on that day. However, the change from baseline represents the difference between paired values only. The data on maximal voluntary strength in the overhead press, leg curl, and latissimus pull exercises are provided in Appendix 2 at http://www.jama.com.

^†Overall analysis of variance, P = .02.

^‡P<.05 vs placebo, no exercise group.

^§Overall analysis of variance, P = .004.