Cell viability of (A) HepG2 cells and (B) L-02 cells treated with three different-sized silica nanoparticles at 20–640 μg/mL for 48 hours. Cell viabilities of (C) HepG2 cells and (D) L-02 cells treated with three different silica nanoparticles for 24, 48, and 72 hours (160 μg/mL) versus control group.
Note: *P < 0.05.
Abbreviations: FITC, fluorescein isothiocyanate; SNP7, size 7 nm silica nanoparticles; SNP20, size 20 nm silica nanoparticles; SNP50, size 50 nm silica nanoparticles.