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Apoptosis of SKM-1 cells treated with either 2ME alone or loaded with MNPs-Fe3O4 (100:1) for 24 hours. (A) Control. (B) MNPs-Fe3O4. (C) 2 μM 2ME. (D) Copolymer of 2 μM 2ME with MNPs-Fe3O4 (100:1).
Abbreviations: MNPs-Fe3O4, magnetic nanoparticles of Fe3O4; 2ME, 2-methoxyestradiol; PI, propidium iodide; FITC, fluorescein isothiocyanate.
