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Schematic representation of the position of neo-cleavage sites in rF20 mutant proteins. The figure depicts graphically the data presented in Table 3 for each mutation separately. Only the domains for which neo-cleavage sites were identified are numbered. The domains are coded as described in Fig. 1. The position of the mutation is indicated with an asterisk. T, trypsin; C, chymotrypsin; P, plasmin; Th, thrombin; MMP, matrix metalloproteinase; Cat, cathepsin.
