TABLE 1.

Identification of differentially expressed proteins between the miNeg HEK293 cells and miCUL4B HEK293 cells

Spot no.	Protein description	Mr/pI	Matched peptides	Coverage (%)	NCBI accession No.	Mascot score
A. Up-regulated proteins in miCUL4B HEK293 cells
1	Triose-phosphate isomerase 1	26700/6.45	7/20	25	4507645	72
2	Eukaryotic translation initiation factor 3, subunit 2β	36606/5.38	7/33	44	4503513	83
4	Superoxide dismutase 1, soluble	15941/5.70	6/36	85	4507149	151
5	Peroxiredoxin III	25854/6.00	6/17	29	32483377	272
8	Cyclin H	37779/6.73	5/17	21	4502623	63
11	Non-metastatic cells 1, protein (NM23A) expressed in isoform b	17217/5.83	9/27	31	4557797	84
13	Glyoxalase I	20818/5.24	11/31	26	5729842	75
14	Tropomyosin 3 isoform 2	29127/4.75	7/65	33	24119203	96
19	Proteasome α1 subunit isoform 2	29665/6.15	9/35	51	4506179	59
20	Heat shock 70-kDa protein 9B precursor	73922/5.87	31/62	40	24234688	332
30	Heat shock 27-kDa protein 3	16987/5.66	3/27	30	53688	57
31	Aspartyl-tRNA synthetase	57340/6.11	3/6	22	45439306	82
32	NADH dehydrogenase (ubiquinone)1β subcomplex	12082/5.47	2/19	30	4758778	61
33	2B28 protein	35229/5.32	5/18	29	21361517	173
B. Down-regulated proteins in miCUL4B HEK293 cells
3	Eukaryotic translation initiation factor 5A	16917/5.08	4/28	47	4503545	174
16	Heat shock 70-kDa protein 5 (glucose-regulated protein, 78 kDa)	72464/5.07	16/48	40	16507237	173
18	Tripartite motif-containing 47	69600/6.03	6/15	15	54792146	57
25	ATP binding protein associated with cell differentiation	26581/5.61	4/24	19	18104959	75
26	Annexin A5	36042/4.94	11/21	51	4502107	278
28	Sulfotransferase family, member 1	33239/5.42	16/59	49	7657633	67
29	Heterogeneous nuclear ribonucleoprotein K isoform b	51136/5.39	14/37	19	14165435	79