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PPCSE induces HO-1 expression through PDGFR/PI3K/Akt cascade in a PC-PLC/PKCδ/NADPH oxidase/ROS-dependent manner in bEnd.3 cells. Schematic diagram illustrating the proposed signaling pathway involved in PPCSE-induced HO-1 expression in bEnd.3 cells. PPCSE-induced HO-1 expression is mediated by PC-PLC/PKCδ/NADPH oxidase/ROS-dependent PDGFR/PI3K/Akt cascade.
