Table 1. Screen hits (>75% permeable embryos & brood size* >90).
| Target ORF | Gene name | Gene description | NCBI KOG | Human homolog |
| Lipid biosynthesis, modification, or sensing | ||||
| F32H2.5 | fasn-1 | Fatty Acid SyNthase | None | FASN (NP_004095.4) |
| H02I12.8/Y17G9B.3 | cyp-31A2/3 | CYtochrome P450 family | Cytochrome P450 CYP4/CYP19/CYP26 subfamilies | CYP4V2 (NP_997235.3) |
| K10D2.6 | emb-8 | Cytochrome P450 NADPH-reductase | NADP/FAD dependent oxidoreductase | POR (NP_000932.3) |
| W01A11.2 | dgtr-1 | (DGAT-Related); putative Acyl-CoA:diacylglycerol acyltransferase | Acyl-CoA:diacylglycerol acyltransferase | Related to enzymes in the DGAT/MGAT family |
| C32E8.8 | ptr-2 | PaTched Related | Patched superfamily | PTCHD family |
| Glycosylation, chitin-binding | ||||
| C07G2.1/B0280.5 | cpg-1/cpg-2 | Chondroitin ProteoGlycan | None | None |
| Meiosis/Mitosis | ||||
| T05G5.7 | rmd-1 | Regulator of Microtubule Dynamics | Uncharacterized conserved protein | Unclear |
| Uncharacterized | ||||
| T01H3.4 | perm-1 | PERMeable eggshell | None | None |
| K07A12.2 | egg-6 | EGG sterile | Leucine rich repeat | None |
| C44B12.1 | perm-2 | PERMeable eggshell | None | None |
*Brood size = total number of hatched larvae, permeable embryos, and dead embryos on the Day1 and Day2 plates combined.