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. Author manuscript; available in PMC: 2012 Sep 14.
Published in final edited form as: Chem Rev. 2011 Jul 25;111(9):5492–5505. doi: 10.1021/cr2000509

Figure 6.

Figure 6

Screening for isolates that cause developmental/morphological changes in S. coelicolor. First column: 5 ul of dense spore solutions of WT Streptomyces coelicolor M145 (alone in row 1) and various wild Streptomyces isolates were spotted 1 cm apart on R2YE agar. Isolates were screened for their ability to influence S. coelicolor morphology. Second column: Wild isolates were grown as lawns on agar, and extracted with ethanol. Extracts were then tested for morphological activity against a lawn of S. coelicolor (pictured) after 48 hours. Third column: Close-ups of the same wells shown in column 2 after 72 hours. Row one shows a control colony of S. coelicolor and a well with extract from an uninoculated plate. The extracts showed various activities against S. coelicolor (Figure provided by Matt Traxler).