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Meropenem measured cerebrospinal fluid (CSF)/predicted plasma concentration ratio: A) measured CSF/predicted plasma concentration ratio versus time of CSF collection (9 CSF sample data points; duplicate CSF samples collected 0.5 hours after dose overlap); B) measured CSF/predicted plasma concentration ratio versus white blood cell count (WBC) in the CSF (8 CSF sample data points with documented CSF WBC; duplicate CSF samples collected 0.5 hours after dose overlap).
