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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Cell Microbiol. 2011 Aug 24;13(10):1586–1600. doi: 10.1111/j.1462-5822.2011.01643.x

Figure 4. Francisella hypercytotoxic mutants require phagosomal escape to induce AIM2-mediated pyroptosis.

Figure 4

(A) Cell death and (B) IL-1β secretion by infected wild type BMDMs at 10 hrs post infection. BMDMs were infected with the indicated bacterial strains at an effective MOI of 20. Data is representative of 3 independent experiments. * p value < 0.05 using the Student's t test.