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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Neurogastroenterol Motil. 2011 Aug 1;23(10):949–e409. doi: 10.1111/j.1365-2982.2011.01760.x

Figure 2. Histamine altered contractility in simian and murine colonic longitudinal smooth muscle.

Figure 2

(A) Representative mechanical trace illustrating that histamine (10 μmol L-1) caused an increase in contractile force in simian colonic muscle. (B) Application of histamine (10 μmol L-1) resulted in a transient decrease in the force of contractions in murine colonic smooth muscle in 8 out of 15 tissues tested. (C) Summary data of area under the curve (AUC) for 5 min recording before and after histamine treatment from murine (n=15) and simian colonic smooth muscle (n=4). * denotes P<0.05.