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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Neurogastroenterol Motil. 2011 Aug 1;23(10):949–e409. doi: 10.1111/j.1365-2982.2011.01760.x

Figure 4. Histamine altered membrane potential in simian and murine colonic longitudinal smooth muscle.

Figure 4

Representative traces illustrating that histamine (10 μmol L-1) caused depolarization in the absence (A) and presence (B) of TTX (1 μmol L-1) in simian colonic smooth muscle. In contrast, in murine colonic smooth muscle, representative traces show that histamine (10 μmol L-1) induced transient hyperpolarization in the absence (C) and sustained hyperpolarization in the presence (D) of TTX (1 μmol L-1).