Table 2.

Substrate scope

entry	substrate	product	time (h)	yield (%)a	ee (%)b
1c,d	5c	6	48	74	91
2	11 R=Me R′=H	12	72	70	90
3	13 R=H R′=Me	14	72	66	89
4	15 R=Me R′=Me	16	96	51	89
5	17 R=H R′=Ph	18	72	48	86
6	19 R=CO2Et R′=H	20	72	66	90
7e	21 R=CO2Me R′=Me	22	96	37	80
8c,d	23	24	72	54	95
9	25	26	72	42	88
10d	27	28	72	77	90
11	29	30	72	70f	89f

^aIsolated yields after chromatography on silica gel.

^bDetermined by HPLC using commercial chiral columns.

^c10 mol% 10 + 8.

^dThe absolute stereochemistry of 24 and derivatives of 28 and 6 were determined by Xray crystallography and that of all other products was assigned by analogy.

^e20 mol% 10 + 8.

^fDetermined on the free alcohol.