Table 1.
Demographic and clinical features of nine BREF patients
| Patient no. | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
|---|---|---|---|---|---|---|---|---|---|
| Sex (M/F) | F | M | F | M | M | F | F | M | F |
| Age (years) | 65 | 46 | 39 | 52 | 58 | 28 | 53 | 33 | 29 |
| Age at onset | 62 | 39 | 39 | 52 | 58 | 26 | 53 | 33 | 29 |
| Other headaches | No | Migraine | Migraine | Tensión-type | Migraine | No | No | No | Migraine |
| Interictal Pain | No | No | No | No | No | Circumscribed | Circumscribed | No | No |
| Pain paroxysms | |||||||||
| Head side | Left | Right | Left | Left | Right | Left | Right | Right | Left |
| Site of origin | Eye | Forehead | Eye | Eye | Eye | Frontal | Frontal | Frontal | Eye |
| Site of end | Occipital | Occipital | Occipital | Occipital | Parietal | Parietal | Occipital | Occipital | Occipital |
| Trajectory | Linear | Linear | Linear | Linear | Linear | Linear | Linear | Linear | Linear |
| Character | Stabbing | Stabbing | Burning | Stabbing | Pressing | Stabbing | Electric | Stabbing | Stabbing |
| Duration (sec) | 5 | 5 | 10 | 3 | 15 | 3 | 3 | 15 | 5 |
| Intensity (VAS) | 6 | 7 | 10 | 4 | 5 | 9 | 9 | 7 | 5 |
| Accompaniments | No | No | No | No | Tearing itching eye | Rhinorrhoea itching eye | No | No | Itching eye |
| Triggers | No | No | No | No | Physical activity | Touch | No | No | No |
| Frequency | 8/day | 1–2/week | 1/week | 1/day | 1/day | 20/day | 20/day | 12/day | 1/day |
| Temporal pattern | Chronic | Remitting | Remitting | Chronic | Remitting | Chronic | Chronic | Chronic | Chronic |
| Therapy | Amitriptyline | No | No | Amitriptyline | Gabapentin | Lamotrigine | Carbamazepine | Gabapentine | Gabapentine |
| Response | Complete | Complete | No | Complete | Complete | Partial | Partial | ||
M male, F female, VAS visual analogical scale (0: no pain, 10: the worst imaginable pain)