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Structural relationship between members of the NSD family. Major domains are highlighted: NID, nuclear receptor binding domains, ligand independent (light purple) or dependent (dark purple); PWWP, chromatin associated domains; HMG, high mobility group; PHD, plant homeo domain; SET, set domain with pre- and post-motifs; C5HCH, chromatin associated zinc fingers. Numbers represent the number of amino acids in each NSD protein. Not drawn to scale.
